AAS-6: Nandrolone Derivatives Fitness&Beast Rating: 8.6 / 10
AAS-6: Nandrolone Derivatives
05/12/2018 9:00 AM
AAS-6: NANDROLONE DERIVATIVES
It was firstly put in the market as Nandrolone Phenylpropionate molecule having a trade name of Durabolin by Organon Company.
But it gained popularity when it was put in the market in the trade name of Deca Durabolin. It carried decanoate ester (Nandrolone Decanoate) in this form. It was so famous that all nandrolone molecules were known as Deca.
Nandrolone hormone may attach to many esters especially phenylpropionate, decanoate and cypionate.
Nandrolone has a reputation as very strong bulking hormone and is also used in treatment of some diseases.
Nandrolone is in the form of 19-nortestosterone. It doesn’t have carbon atom in the 19th position and this difference makes it pretty different AAS. Anabolic effect is more than testosterone but androgenic effect is %37 less than testosterone.
Testosterone is accepted as reference molecule in the anabolic-androgenic ratios and the reference points are 100-100 so this means that nandrolone’s androgenic point is only 37. The reason of this low point is about the metabolism of the molecule.
Nandrolone is metabolised to DHN (dihydronandrolone) not to DHT (dihydrotestosterone).
Its estrogenic effect is lower than testosterone and interaction with aromatase enzyme is %20 of testosterone is.
Nandrolone is accepted as active progestin and this causes some of its side effects.
Main effect mechanisms of Nandrolone:
-Increase in protein synthesis
-Inhibition of glucocorticoids
-Increase in production of IGF-1
-Increase in nitrogen retention
-Increase in red blood cell count
-Increase in collagen synthesis
-Enhance bone mineral density
The first five of these mechanisms are also detected in other AAS’s but increase in nitrogen retention is dominant for nandrolone. %16 of muscle tissue is composed of nitrogen and any decrease in nitrogen retention may cause catabolism.
Nandrolone hormone converts this condition to anabolic phase effectively. The effects of nandrolone on collagen and bone tissues are not found in other AAS’s. It especially has beneficial effect in relieving the joint and tendon pain.
Even some athletes prefer nandrolone mostly for this advantage. It is used as a treatment option in diseases with the muscle wasting, fatigue and weakness due to elderliness. It is also used in patients with burn injuries and osteoporosis.
Nandrolone has favorable effect on muscle size. The increase in muscle size is not acute as it is for oxymetholone but it is long acting and has high quality. Nandrolone has also positive effect in the augmentation of strength and lipolysis.
Side Effects of Nandrolone
Estrogenic side effects: Aromatization is lower than testosterone. However gynecomastia, water retention and hypertension may be seen. The important property of nandrolone is that it has a structure of progestin so it may bind to progestin receptors, cause gynecomastia in sensitive individuals. Aromatase inhibitors like Anastrozol and selective estrogen receptor modulators (SERM) like Tamoxifen can be used in treatment for treatment of gynecomastia.
Androgenic side effects: Baldness and acneiform lesions may be seen especially in sensitive individuals. 5-alpha reductase inhibitors aren’t useful in the treatment, they even increase the androgenic effects.
Cardiovascular side effects: The decrease in HDL level is more than testosterone.
Testosterone supression: Nandrolone is the hormone which mostly supresses testosterone. Single 100 mg dose of it supresses testosteron in %100 ratio. For this reason exogenous testosterone molecule must be given while using nandrolone. PCT must also be applied.
Effect on liver: It doesn’t have toxic effect on liver.
Now we can have a look at the molecules related with nandrolone.
Nandrolone Phenylpropionate is the first produced molecule and trade name is Durabolin. Nandrolone Decanoate is put to the market later and trade name is Deca Durabolin.
They are named according to the esters binding to nandrolone hormone. Decanoate is a large ester and this decreases its speed in entering the blood circulation.
By this way frequent injection necessity is avoided. Deca Durabolin is used in the dose of 200-300 mg/week by athletes.
Trenbolone Acetate – Trenbolon Enanthate
Trenbolone is 19-nortestosterone like nandrolone, the difference comes from the double bonds in the 9th and 11th carbon atoms.
By this way its affinity to bind to androgen receptors increases, metabolism decreases and it has a chance to avoid aromatization.
These changes make the trenbolone one of the strongest anabolic molecules. Its anabolic/androgenic value is 500/500. This is really incredible and very high.
Finajet – Finaject
Finajet or Finaplix are the trade names of Trenbolone Acetate which has small and short ester and half-life of only two days. For this reason frequent injection is needed.
Trenbolone has an unique property which other AAS’s don’t have: It increases the benefits gained by natural nutrition which we consume daily.
Even the nutrition style isn’t altered, we get the maximum gain from our nutrition by utilizing trenbolone.
It is the most effective AAS which is used in cutting cycle since the diet in cutting cycle leads to decrease in lean muscle ratio in some degree and trenbolone prevents this decrease.
It is so useful in this manner. It is also important in bulking cycle since provides great increase in muscle mass and this is so clean enhancement: an increase without water retention.
It also boosts muscle durability and strength. Trenbolone acetate is usually taken 50-100 mg/ every other day.
It is trenbolone hexahydrobenzylcarbonate. It is a trenbolone with a different ester.
The main difference from Finajet (trenbolone acetate) is that Parabolan carries an ester which has a slow release.
Trenbolone enanthate is similar to Parabolan.
Parabolan can be used as a treatment option for humans but the other two are spared for treatment of animals.
Parabolan enjection form is 76 mg/ml and carries 50 mg trenbolone actively. It used 3-4 times/week frequently.
In the enanthate form there is 100-200 mg/ml and it is used twice a week as a total 200-400 mg dose range. 8-10 weeks usage is common.
Trenbolone can ve accepted as the most effective AAS.
I have been finishing my articles about AAS’s by this writing. I want to review some cycle programmes that can be maintained in my next article…